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Varicalla-Zoster Virus DNA in CSF & Arteries in Delayed Contralat Hemiplegia:Evid for Viral Invasion of Cerebr Art Neurol 47:569-570, Melanson,M.,et al, 1996 See this aricle in Pubmed Article Abstract A 78 year old woman presented with a right basal ganglia infarct 6 weeks after a left herpes zoster ophthalmicus.MR angiography showed focal segmental stenosis of the proximal segments of the anterior,middle and posterior cerebral arteries.Varicella DNA was detected in the CSF by polymerase chain reaction(PCR).Treated with dexamethasone and acyclovir without improvement,she died one month later.There was focal endarteritis in the left anterior,middle and posterior cerebral arteries at autopsy. Varicella DNA was detected by PCR of extracts from these vessels but not from the arteries on the right side.This study provides further evidence that the vasculopathy after herpes zoster ophthalmicus results from direct viral invasion of the vessel wall.

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(click to filter results - removes previous filter) arteritides cerebral infarction cerebrospinal fluid cerebrospinal fluid,abnormal cerebrovascular accident cerebrovascular accident,delayed onset hemiplegia herpes zoster herpes zoster,ophthalmicus MRI MRI,abnormal MRI,angiography polymerase chain reaction varicella zoster virus varicella zoster virus,vasculopathy vasculitides vasculopathy

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